In short

  • Losec is the branded version of Omeprazole and is described as a proton pump inhibitor that reduces stomach acid production.
  • Losec is described as prescription-only in the UK, while 20mg Omeprazole tablets are described as available over the counter.
  • The source recommends considering lifestyle changes such as avoiding late or large meals, reducing smoking and alcohol, and losing weight where relevant.

What is Losec?

Losec is the branded version of Omeprazole. Omeprazole is one of the most commonly prescribed medications in the UK. It is used for the treatment of acid reflux. Acid reflux is caused by stomach acid entering the oesophagus (the food pipe). The oesophagus is not designed for contact with acid, so this can cause irritation and damage to the tissues of the oesophagus producing painful and uncomfortable symptoms such as heartburn. Losec works by blocking part of the mechanism needed for the production of stomach acid, this reduces the amount of acid produced. In this way, Losec effectively decreases the chance of acid reflux. 

Can you buy Losec over the counter in the UK?

Losec is not available over the counter in the UK, it is only available on prescription. However, 20mg tablets of Omeprazole are available over the counter. If you want Losec specifically or a higher dose of Omeprazole, you will need to obtain a prescription. It is recommended that you try over the counter treatments before seeking prescription medication. 

Alternative treatments

Losec is a type of PPI. Other PPIs are also available on prescription including:

  • Esomeprazole (Nexium)
  • Lansoprazole
  • Pantoprazole

Esomeprazole is also available over the counter in 20mg tablets.

H2 antagonists are available on prescription for the treatment of acid reflux, but Ranitidine is now available at low-doses (75mg) over the counter. 

More common over the counter acid reflux treatments include antacids, such as Rennies, and alginates, such as Gaviscon. Antacids work by neutralising the stomach acid, whereas alginates form a gel-like layer on top of the stomach acid, which helps to protect the oesophagus. 

A range of herbal treatments and alternative medicines may claim to alleviate acid reflux, but these substances do not have the same evidence-base as conventional medicine, so should be used with caution. It is recommended that you use conventional medicine where possible. If you are concerned about side effects, you can speak to your pharmacist or doctor who may be able to recommend some alternatives.

It is recommended that everyone with acid reflux considers making lifestyle changes. Acid reflux may seem like a mild condition that only causes a bit of discomfort. However, the damage to your oesophagus makes you much more likely to suffer from oesophageal cancer. Medications can help to protect against this, but often the underlying cause of your acid reflux can be resolved (at least partially) through lifestyle changes, further reducing your risk. Making the following changes may help to resolve or reduce your acid reflux:

  • Avoid eating late at night or lying down soon after eating – after a meal, the muscle that closes the top of your stomach may be more relaxed, and lying down allows stomach acid to leak out.
  • Avoid eating large meals – large meals increase the pressure inside your stomach, which can push stomach acid upwards towards the oesophagus
  • Stop smoking, or reduce the amount you smoke – smoking causes the muscle that seals the top of your stomach to relax, meaning that stomach acid is able to escape
  • Lose weight – carrying excess body fat – particularly around the abdomen, increases the pressure inside your abdominal cavity. This encourages stomach acid to move upwards into the oesophagus.
  • Avoid alcohol or reduce alcohol intake – like smoking, alcohol also causes the sealing muscle at the top of your stomach to relax, making acid reflux much more likely. 

Making these changes may help to reduce your acid reflux and your need for medications.

Sources

References

2 sources were selected to match the subject of this article. Link destinations were checked twice when added. This does not mean every statement has been individually source-mapped or clinically approved.

  1. Losec Capsules 20mg — Patient Information Leaflet

    electronic medicines compendium (emc) · HTML · patient information leaflet · Last updated on emc 20 February 2026 · Link destination checked 5 September 2026

  2. Omeprazole: a medicine to treat heartburn and indigestion

    NHS · HTML · medicine guidance · Link destination checked 5 September 2026

Reference links open the cited source pages. If you spot something out of date, tell our content team.

Who wrote this

Written and reviewed by our team

Authored by

Ian Coakley, Content Writer

Content Writer

Ian is Simple Online Pharmacy’s Content Writer; he joined the team in 2021. He has had a varied career path, starting as a science communicator and freelance editor and writer. While Ian has been published in some independent outfits, Simple Online Pharmacy marks his first foray into writing for a corporate entity.

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Medically reviewed by

Karim Nassar, Co-Founder, Pharmacist & Author

Karim Nassar

Co-Founder, Pharmacist & Author

Karim is a registered pharmacist with the General Pharmaceutical Council (GPhC) and was a founding member of Simple Online Healthcare in 2015. With a Master of Pharmacy degree from Strathclyde University, Karim brings a strong foundation in pharmaceutical care and a passion for leveraging digital solutions to improve patient access to healthcare.

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