In short

  • It is a type of medication known as a proton pump inhibitor (PPI), which means that it works by blocking one of the stages of stomach acid production.
  • This reduces the amount of stomach acid and should help to prevent acid reflux symptoms, which occur as a result of stomach acid irritating the oesophagus (the food pipe).
  • Losec is the branded version of Omeprazole.

What is Omeprazole?

Omeprazole is a popular and highly effective treatment for acid reflux and GORD (gastro-oesophageal reflux disease). It is a type of medication known as a proton pump inhibitor (PPI), which means that it works by blocking one of the stages of stomach acid production. This reduces the amount of stomach acid and should help to prevent acid reflux symptoms, which occur as a result of stomach acid irritating the oesophagus (the food pipe). Losec is the branded version of Omeprazole.

Can you buy Omeprazole over the counter in the UK?

10mg and 20mg tablets of Omeprazole are available over the counter in the UK, but if you need a higher dose (up to 40mg daily), it is recommended that you speak to your GP or an online pharmacy like Simple Online Pharmacy. Omeprazole is a highly effective treatment, but it is recommended that you try over the counter options first. Omeprazole is also commonly prescribed to counteract side effects of other drugs, that may cause acid reflux or irritation of the stomach.

Alternative treatments

Over the counter treatments for acid reflux include antacids, which neutralise the stomach acid and alginates, which help to form a gel layer on top of the acid, which helps to protect the oesophagus. 

There are also a range of acid reflux medications available on prescription:

  • Other PPIs including Esomeprazole (Nexium), Lansoprazole and Pantoprazole.
  • Ranitidine (Zantac) is a different type of acid reflux medication known as an H2 antagonist. It works by blocking certain receptors on cells that produce stomach acid. This helps to reduce the amount of stomach acid that is released. 

Esomeprazole and Ranitidine are also available at low doses over the counter.

Sources

References

2 sources were selected to match the subject of this article. Link destinations were checked twice when added. This does not mean every statement has been individually source-mapped or clinically approved.

  1. Omeprazole: a medicine to treat heartburn and indigestion

    NHS · HTML · medicine guidance · Link destination checked 5 September 2026

  2. Pyrocalm Control 20mg Gastro-Resistant Tablets — Patient Information Leaflet

    electronic medicines compendium (emc) · HTML · patient information leaflet · Last updated on emc 23 January 2026 · Link destination checked 5 September 2026

Reference links open the cited source pages. If you spot something out of date, tell our content team.

Who wrote this

Written and reviewed by our team

Authored by

Hywel McGlinchy - Pharmacist and Medical Writer

Pharmacist / Content Writer

Hywel has been a registered pharmacist since 2017; he started with Simple Online Pharmacy in 2020. Hywel was responsible for helping review and author accurate site content. He worked with our GPs to make sure all aspects of the medications mentioned are covered.

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Medically reviewed by

Karim Nassar, Co-Founder, Pharmacist & Author

Karim Nassar

Co-Founder, Pharmacist & Author

Karim is a registered pharmacist with the General Pharmaceutical Council (GPhC) and was a founding member of Simple Online Healthcare in 2015. With a Master of Pharmacy degree from Strathclyde University, Karim brings a strong foundation in pharmaceutical care and a passion for leveraging digital solutions to improve patient access to healthcare.

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Sources cited

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